Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

Published in Molecular Psychiatry, 2019

Using two independent datasets from genotyped cohorts (UK Biobank and electronic medical record (EMR) in Vanderbilt University Medical Center), we quantified the heritability estimates of suicide attempts. We also showed the shared genetic basis of suicide attempts and other phenotypes.

suicide attempt paper figure 2

Reference: D. M. Ruderfer, C. G. Walsh, M. W. Aguirre, Y. Tanigawa, J. D. Ribeiro, J. C. Franklin, M. A. Rivas, Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide. Mol Psychiatry. 25(10), 2422-2430 (2020). https://doi.org/10.1038/s41380-018-0326-8