[Preprint] Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank

Preprint posted on bioRxiv, 2020

In this study led by Guhan Venkataraman, we characterized the genetic associations between HLA allelotypes and comprehensive human disease phenotypes in UK Biobank.

HLA figure 1

HLA association map app is available as a part of Global Biobank Engine.

Reference: G. R. Venkataraman, J. E. Olivieri, C. DeBoever, Y. Tanigawa, J. M. Justesen, M. A. Rivas, Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank. bioRxiv, 2020.05.28.119669 (2020). https://doi.org/10.1101/2020.05.28.119669