Power of inclusion: Enhancing polygenic prediction with admixed individuals
Date:
The STATGEN 2024 conference on Statistics in Genomics and Genetics is hosted by the American Statistical Association (ASA) Section on Statistics in Genomics and Genetics (SSGG). Yosuke presented in a session on Translation and Transferability of Polygenic Risk Scores to Complex Data Scenarios.
Slides
References
- Tanigawa and Kellis. Power of inclusion: Enhancing polygenic prediction with admixed individuals. Am J Hum Genet. 2023
- Qian et al. A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank. PLoS Gen. 2020.
- Sparse polygenic scores from individual-level data, BASIL algorithm
- Kachuri et al. Principles and methods for transferring polygenic risk scores across global populations. Nat Rev Genet. 2023.
- Review on multi-ancestry-aware PGS methods
- O’Sullivan et al. Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation. 2022
- Perspectives on how PGS may inform clinical practice